A regional metamorphic gradient from upper greenschist to granulite facies is identified south of the Grenville front in the Double Mer – Lake Melville area of eastern Labrador. Mineral assemblages in politic–granitic gneiss, amphibole-bearing quartzo-feldspathic gneiss, and coronitic metagabbro allow three major metamorphic domains to be established. These are collectively divisible into 11 subdomains. Geothermobarometry applied to the higher grade domains suggests that each is characterized by specific P–T conditions, which achieved 1000–1100 MPa and 700–800 °C in the deepest level rocks.The problem of reconciling geochronological data (which record a major orogenic event at 1650 Ma) with the occurrence of high-grade mineral assemblages in 1426 Ma metagabbro (which suggests a pervasive Grenvillian event) is discussed in terms of three models. The preferred model envisages crustal stabilization at 1650–1600 Ma to give high-grade mineral assemblages seen in the host rocks and with which mineral assemblages in coronitic metagabbro equilibrated after their emplacement at 1426 Ma. During Grenvillian orogenesis (1080–920 Ma) the present structural configuration was achieved by thrust stacking. This imparted a sporadic metamorphic and structural overprint and Grenvillian ages in selected accessory minerals.