Use of an Organic-Clay Mineral Complex for Chromatographic Separation of Optical Isomers
Akihiko Yamagishi, 1985. "Use of an Organic-Clay Mineral Complex for Chromatographic Separation of Optical Isomers", Proceedings of the International Clay Conference Denver, 1985, Leonard G. Schultz, H. van Olphen, Frederick A. Mumpton
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A silica gel coated with a film of Λ-Ru(phen)32+-montmorillonite (phen = 1, 10-phenanthroline) was used as a packing material in high-performance liquid-column chromatography. The resolution of Co(acac)3 (acac = acetyl-acetonato) was studied by varying the flow-rate, the component of an eluting solvent, and the temperature of the column. The column showed remarkable resolution efficiency compared with known column materials, such as natural and synthetic organic polymers. The mechanisms of chirality recognition were interpreted in terms of the intermolecular stacking of Co(acac)3 with pread-sorbed Λ-Ru(phen)32+ either on the external surface or in the interlayer space of the clay film. The column also resolved a wide variety of organic compounds, some of which are key molecules in asymmetric syntheses, such as 2, 2′-binaphthol and phenyl alkyl sulfoxides.
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Proceedings of the International Clay Conference Denver, 1985
The papers included in this proceedings volume are representative of the research on clays being conducted in all parts of the world at the time of publication. Many of the subjects treated are controversial, and although some ideas expressed may not necessarily represent the views of the editors, the referees, or the publisher, they deserve to be brought to the attention of the international clay community.