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We propose an integrated kinematic model with mechanical constrains of the Maipo–Tunuyán transect (33°40′S) across the Andes. The model describes the relation between horizontal shortening, uplift, crustal thickening and activity of the magmatic arc, while accounting for the main deep processes that have shaped the Andes since Early Miocene time. We construct a conceptual model of the mechanical interplay between deep and shallow deformational processes, which considers a locked subduction interface cyclically released during megathrust earthquakes. During the coupling phase, long-term deformation is confined to the thermally and mechanically weakened Andean strip, where plastic deformation is achieved by movement...

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