Regional surveys, including studies of rock chips and aerial radiometrics and magnetics, focused within an area of 400 sq km on the Canning stock, found enrichment in U, Th, and K. Stream-sediment data indicated an anomalous block adjacent to and including the North Canning and Fuller deposits. A subregional soil survey noted overlapping anomalies of eU, xU, Pb, Cu, and Ba in the vicinity of the North Canning deposit. This was confirmed by overlapping anomalies of eU, xU, Pb, Cu, and Ba in the rock-chip survey. Integrated radon and soil helium data were ineffective in delineating drilling targets at the subregional scale. The subregional magnetic, VLF-EM, and resistivity data confirmed the presence of a fractured and crushed zone within the host granite of the North Canning deposit. This interpretation is based on the presence of an overlapping low resistivity zone and a magnetic depression of about 40 gammas. Core holes were sited within an area of 25 sq km that included the North Canning deposit, the leachable-uranium-in-rock-chip anomaly, the aerial radiometric anomaly, and overlapping geochemical (xU, eU, Ba, He, Rn, As, Ni, and Pb) anomalies in the detailed soil survey. These holes, logged with a multispectral (K-U-Th) probe, show zonation of K, eU, and eTh in the monzonite and granitic host rock and indicate both directional and genetic information related to the origin of the uranium deposit.